Singh Laboratory: Translational Neuroscience
The Singh Laboratory is dedicated to understanding the role of cerebral blood vessels in the pathogenesis of neurological disorders. The long-term goal is to develop therapeutic strategies and novel treatments based on these understandings.
Blood vessels in the brain provide nutrition, clear metabolic waste and facilitate neural activity that underlies human cognition. Dysfunctions of the neurovascular system disturb brain homeostasis and independently contribute to pathogenesis in neurological disorders. Active research interests in the lab include neurovascular mechanisms of neurodegeneration in Alzheimer’s disease (AD), ischemic stroke, subarachnoid hemorrhage (SAH), germinal matrix hemorrhage (GMH) and flavivirus encephalitis. The lab is also engaged in developing translational biomarkers and therapeutic targets for AD, SAH and GMH.
Itender Singh, PhD
Assistant Professor of Neurological Surgery
Washington University School of Medicine
Department of Neurological Surgery
660 S. Euclid Avenue, BJCIH, Room 9206
Campus Box 8057
St. Louis, Missouri 63110