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Grants and Clinical Trials by Faculty

 

Increase in number of departmental grants over the past 15+ years

Michael Chicoine

Current Clinical Trials:
“Prospective Multicenter Cohort Study Comparing Extent of Tumor Resection Between Microscopic Transsphenoidal Surgery and Fully Endoscopic Transsphenoidal Surgery for Nonfunctioning Pituitary Adenomas”

“Transsphenoidal Extent of Resection Study (TRANSSPHER)”
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“I-MiND: IMRIS Intraoperative iMRI Neurosurgical Database”

“MSTIE III: Minimally Invasive Surgery Plus rt-PA for Intracerebral Hemorrhage Evacuation”
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Ian Dorward

Current Clinical Trials:

AccuLIF® PROSPECTIVE PATIENT OUTCOMES STUDY

MSTIE III: Minimally Invasive Surgery Plus rt-PA for Intracerebral Hemorrhage Evacuation
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Gavin Dunn

Current Grants:
“The Effect of Checkpoint Blockade Immunotherapy on Malignant Glioma Immunogenicity”
Siteman ACS-IRG
01/01/15 – 12/31/15
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“Immunobiology of Malignant Glioma”
NIH K08
07/01/15 – 06/30/20
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Current Clinical Trials:
“Neoepitope-based Personalized Vaccine Approach in Patients With Newly Diagnosed Glioblastoma”
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Albert Kim

Current Grants:
“Mechanisms of Radiation Resistance in Brain Meningiomas”
Meningioma Mommas
06/01/15 – 05/31/16
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 “Therapeutic epigenetic reprogramming of brain cancer stem cells using microRNAs”
Brain Research Foundation
06/01/15 – 05/31/17
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“Regulation of Brain Cancer Stem Cells by the Anaphase-Promoting Complex”
Concern Foundation
07/01/14 – 06/30/16
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“Mechanisms of Dendrite Morphogenesis by the Anaphase-Promoting Complex”
NIH K08
9/1/2012 – 7/31/2017
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Eric Leuthardt

Current Grants:
“Electrophysiological Studies of Human Attention”
NIH R01
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Current Clinical Trials:
“LAASR: MK-3475 in Combination With MRI-Guided Laser Ablation in Recurrent Malignant Glioma; Laser Ablation After Stereotactic Radiosurgery”
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“MRI-Guided Laser Surgery and Doxorubicin Hydrochloride in Treating Patients With Recurrent Glioblastoma Multiforme”
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“Treatment of Chronic Stroke With IpsiHand”
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“Laser Ablation in Stereotactic Neurosurgery (LAISE): NeuroBlate® Retrospective Registry Monteris”
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“Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System
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David Limbrick

Current Grants:
A randomized controlled trial of anterior versus posterior entry site for cerebrospinal fluid shunt insertion”
PCORI Subcontract with Baylor
01/01/15 – 12/31/15
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“Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation with Syringomyelia”
Patient Centered Outcomes Research Institute (PCORI)
2015 for 45 months
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“MR Elastography and CSF Biomarkers in Post-Hemorrhagic Hydrocephalus”
Hope Center for Neurological Disorders
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“Effects of Cerebrospinal Fluid Diversion on Functional Connectivity in Prematurely-Born Infants with Hydrocephalus”
March of Dimes Prematurity Research Center at Washington University
 
A Pilot Study of Using MRI-Guided Laser Heat Ablation in to Induce Disruption of the Peritumoral Blood Brain Barrier and Enhance Efficacy of Treatment for Pediatric Brain Tumors”
Children’s Discovery Institute
02/01/2016 – 1/31/2019
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“Gene Discovery in Syringomyelia and Chiari I Malformation”
Spinal Cord Injury/Disease Research Program
 
Current Clinical Trials:

“Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia”
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“The CSF Shunt Entry Site Trial”
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Zack Ray

Current Grants:
 “An Implantable Transient Electronic Nerve Stimulation Device based on Transient Electronics”
DARPA subcontract with Transient Electronics
11/18/14 – 02/17/17
 
“Development of a macro-sieve interface for chronic communication in the primate peripheral nervous system”
DARPA (PI: Moran)
03/31/15 – 03/31/18
 
“Nerve Transfers for Improved Hand Function following Cervical Spinal Cord Injury”
Department of Defense
08/15/15 – 08/14/19
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“Evaluation of Axonal Integrity Using Diffusion Tensor Imaging”
NIH K23
09/01/13-08/31/18       
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“Diffusion basis spectrum imaging predicts neuroinflammation and axonal loss in acute and chronic spinal cord injury” – Zack Ray
University of Missouri Spinal Cord Injury Research Program
10/01/15-09/30/17                     

Current Clinical Trials:
“Restoring Hand Function Using Nerve Transfers in Persons with Spinal Cord Injury”

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“A Phase IIB, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Staphylococcus Aureus 4-Antigen Vaccine (SA4Ag) in Adults Undergoing Elective Posterior Instrumented Lumbar Spinal Fusion Procedures”

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“Safety and Efficacy of Pulsed Electromagnetic Fields (Cervical-Stim) as an Adjunct to Enhance Union in Conservatively Treated Type II Fractures of the Odontoid Process”

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“Diffusion Tensor Imaging to Assess the Functional Outcomes of Adults with Cervical Spinal Cord Injuries”

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 “Bone Marrow Aspirate Concentration in Posterior Cervical Fusion (BMAC)”

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“Riluzole in Spinal Cord Injury Study (RISCIS)”

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“Diffusion Tensor Imaging to Assess the Functional Outcomes of Adults With Cervical Spinal Cord Injuries”

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“DuraSeal Exact Spine Sealant System Post-Approval Study (DuraSeal PAS)”

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“Pivotal IDE Study of the BRYAN(R) Cervical Disc Prosthesis in the Treatment of DDD Versus ACDF”

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“The INSPIRE Study: Probable Benefit of the Neuro- Spinal Scaffold for Treatment of AIS A Thoracic Acute Spinal Cord Injury”

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Gregory Zipfel

Current Grants:
Translating Endogenous Vascular Protective Cascades into Therapy for Aneurysmal Subarachnoid Hemorrhage”
NIH R01
09/01/15 – 08/30/20
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“Washington University Neurosurgery Resident Research Education Program”
NIH R25
09/30/15 – 06/30/20
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