Gregory J. Zipfel, MD

Gregory J. Zipfel, MD

Chair, Department of Neurosurgery

Ralph G. Dacey Distinguished Professor of Neurosurgery

Neurosurgeon-in-Chief, Barnes-Jewish Hospital

Castle Connolly Top Doctor

Specialties

  • Brain aneurysms and vascular malformations
  • Carotid stenosis, moyamoya disease, and other vascular diseases causing stroke
  • Skull base tumors including meningiomas and acoustic neuromas
  • Pituitary Tumors
  • Minimally invasive surgery including “keyhole” and endoscopic techniques

Call 314-362-3577 for Patient Appointments



I strive to provide leading-edge surgical care to my patients, while also assuring that they and their families feel supported and individually cared for throughout.

Dr. Zipfel

Education

BS, Biology, University of Illinois, Champaign
Urbana, Illinois
1987-1991

MD, Northwestern University Medical School
Chicago, Illinois
1991-1995

Residency

Resident, Neurological Surgery
University of Florida
Gainesville, Florida
1995-2003

Fellowship

Post-doctoral Research Fellow, Neurology
Washington University School of Medicine 
St. Louis, Missouri 
1998-2000

Cerebrovascular and Skull Base Surgery Fellow
Department of Neurological Surgery, University of Miami
Miami, Florida
2003-2004



Research focus

  1. Examine effects of amyloid-β on cerebral arteriole function and assessing its contribution to ischemic brain injury, cerebral amyloid angiopathy, and Alzheimer’s Disease.
  2. Explore mechanisms that underlie cerebral vasospasm and cognitive deficits following aneurysmal subarachnoid hemorrhage.

View research, publications and collaborations »

Zipfel Lab

Zipfel Lab

The Zipfel Lab aims to understand the mechanisms driving acute and chronic cerebrovascular diseases, identify new molecular targets, and develop novel therapies that will improve the lives of our patients.


Honors & leadership roles

  • Ralph G. Dacey Distinguished Endowed Professor of Neurological Surgery
  • Past Co-Chair, Editorial Board for Journal of Neurosurgery
  • Past Chair, Joint Cerebrovascular Section of the AANS/CNS
  • Board of Directors, Neurosurgery Research and Education Foundation
  • Vice-Chair of Research Committee, Neurosurgery Research and Education Foundation
  • Director, Emerging Investigator Mentoring Program of the American Academy of Neurological Surgery
  • Co-Director, NIH-funded National Neurosurgeon Research Career Development Program
  • Member, Advisory Council for Neurological Surgery for the American College of Surgeons
  • Member, STROKE Council / Scientific Statement Oversight Committee of the American Stroke Association
  • Member, Medical Advisory Board of the Brain Aneurysm Foundation
  • Standing Member, NIH Study Section (Neurological Sciences and Disorders-Clinical)

Board certification

Board certified, American Board of Neurological Surgery


Hospital appointments

Barnes-Jewish Hospital
St. Louis Children’s Hospital
Missouri Baptist Medical Center