Department of  Neurosurgery
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Benjamin Plog, MD, PhD

Position: PGY1
Hometown: Clifton Park, NY
Medical School: University of Rochester School of Medicine and Dentistry
Undergraduate: University of Rochester
Clinical/Research Interests: Neuro-oncology, Skull-base, Neurotrauma, Spine, Cerebrospinal Fluid Hydrodynamics


  •  Iliff, J.J., Chen, M.J., Plog, B.A., Zeppenfeld, D.M., Soltero, M., Yang, L., Singh, I., Deane, R., & Nedergaard, M. Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury. Journal of Neuroscience. 2014, Dec; 34(49): 16180-16193. Cited in PubMed; PMID: 25471560.

  • Iliff, J.J., Wang, M., Liao, Y., Plog, B.A., Peng, W., Gundersen, G.A., Benveniste, H., Vates, G.E., Deane, R., Goldman, S.A., Nagelhus, E.A., & Nedergaard, M. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta. Science Translational Medicine. 2012, Aug; 4(147): 147ra111. Cited in PubMed; PMID: 22896675.

  • Iliff, J.J., Wang, M., Zeppenfeld, D.M., Venkataraman, A., Plog, B.A., Liao, Y., Deane, R., & Nedergaard, M. Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain. Journal of Neuroscience. 2013, Nov; 33(46): 18190-18199. Cited in PubMed; PMID: 24227727.

  • Kress, B.T., Iliff, J.J., Xia, M., Wang, M., Wei, H.S., Zeppenfeld, D., Xie, L., Kang, H., Xu, Q., Liew, J.A., Plog, B.A., Ding, F., Deane, R., & Nedergaard, M. Impairment of paravascular clearance pathways in the aging brain. Annals of Neurology. 2014, Dec; 76(6): 845-861. Cited in PubMed; PMID: 25204284.
  • Louveau, A.*, Plog, B.A.*, Antila, S.*, Alitalo, K., Nedergaard, M., & Kipnis, J. Understanding the functions and relationships of the glymphatic system and meningeal lymphatics. The Journal of Clinical Investigation. 2017, Sep; 127(9): 3210-3219. Cited in PubMed; PMID: 28862640.
  • Petraglia, A.L., Plog, B.A., Dayawansa, S., Chen, M., Dashnaw, M.L., Czerniecka, K., Walker, C.T., Viterise, T., Hyrien, O., Iliff, J.J., Deane, R., Nedergaard, M., & Huang, J.H. The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: a novel mouse model of chronic traumatic encephalopathy. Journal of Neurotrauma. 2014, Jul; 31(13): 1211-1224. Cited in PubMed; PMID: 24766454. Pub Status: Published. Petraglia, A.L., Plog, B.A., Dayawansa, S., Dashnaw, M.L., Czerniecka, K., Walker, C.T., Chen, M., Hyrien, O., Iliff, J.J., Deane, R., Huang, J.H., & Nedergaard, M. The pathophysiology underlying repetitive mild traumatic brain injury in a novel mouse model of chronic traumatic encephalopathy. Surgical Neurology International. 2014, Dec; 5(1): 184. Cited in PubMed; PMID: 25593768.

  • Pierre C.A., Plog, B.A., Srinivasan V., Srinivasan K., Petraglia A.L., & Huang J.H. Tree stand falls: A persistent cause of neurological injury in hunting. World Journal of Clinical Cases. 2014, Aug; 2(8): 345-350. Cited in PubMed; PMID: 25133145.
  • Plog, B.A., Pierre C.A., Srinivasan V., Srinivasan K., Petraglia A.L., & Huang J.H. Neurologic injury in snowmobiling. Surgical Neurology International. 2014, Jun; 5(1): 87. Cited in PubMed; PMID: 25024887.
  • Plog, B.A.*, Dashnaw, M.L.*, Hitomi, E., Peng, W., Liao, Y., Lou, N., Deane, R., & Nedergaard, M. Biomarkers of traumatic injury are transported from brain to blood via the glymphatic system. Journal of Neuroscience. 2015, Jan; 35(2): 518-526. Cited in PubMed; PMID: 25589747.
  • Plog, B.A., & Nedergaard, M. Why have we not yet developed a simple blood test for TBI?. Expert Review of Neurotherapeutics. 2015, Mar; 15(5): 465-468. Cited in PubMed; PMID: 25821902.

  • Plog, B.A., & Nedergaard, M. The glymphatic system in central nervous system health and disease: Past, present, and future. Annual Review of Pathology: Mechanisms of Disease. 2018, Jan; 13(1): 379-394. Cited in PubMed; PMID: 29195051.

  • Plog, B.A., Moll, K.M., Kang, H., Iliff, J.J., Dashnaw, M.L., Nedergaard, M., & Vates, G.E. A novel technique for morphometric quantification of subarachnoid hemorrhage-induced microglia activation. Journal of Neuroscience Methods. 2014, May; 229(1): 44-52. Cited in PubMed; PMID: 24735531.

  • Rangroo-Thrane, V., Thrane, A.S., Plog, B.A., Thiyagarajan, M., Iliff, J.J., Deane, R., Nagelhus, E.A., & Nedergaard, M. Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain. Scientific Reports. 2013, Sep; 3(1): 2582. Cited in PubMed; PMID: 24002448.

  • Srinivasan V., Pierre C., Plog B., Srinivasan K., Petraglia A.L., & Huang J.H. Straight from the horse's mouth: neurological injury in equestrian sports. Neurological Research. 2014, Oct; 36(10): 873-877. Cited in PubMed; PMID: 24725290.

  • Thrane, A.S., Rangroo-Thrane, V., Plog, B.A., & Nedergaard, M. Filtering the muddied waters of brain edema. Trends in Neurosciences. 2015, Jun; 38(6): 333-335. Cited in PubMed; PMID: 26008121.