Department of  Neurosurgery
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Ananth Vellimana, MD

Ananth Vellimana, MDPosition: PGY 7
Hometown: Trivandrum, India
Medical School: All India Institute of Medical Sciences, New Delhi, India
Clinical/Research Interests: Cerebrovascular, neuro-oncology
Departmental Awards:
2016-2017 – Department of Neurosurgery T.S. Park Board Score Award
2016-2017 – Department of Neurosurgery Research Symposium Presentation Award – Basic Science
2017-2018 – Department of Neurosurgery T.S. Park Board Score Award

Publications:
  • Vellimana AK, Diwan D, Clarke J, Gidday JM, Zipfel GJ. SIRT1 Activation: A potential strategy for harnessing endogenous protection against delayed cerebral ischemia after subarachnoid hemorrhage. Neurosurgery (In Press)

  • Vellimana AK, Zhou ML, Singh I, Aum DJ, Nelson JW, Athiraman U, Han BH, Zipfel GJ. Matrix metalloproteinase-9: A key contributor to delayed cerebral ischemia after subarachnoid hemorrhage. Annals of Clinical and Translational Neurology Ann Clin Transl Neurol. 2017 Oct 30;4(12):865-876

  • Mahlokozera T*, Vellimana AK*, Li T*, Mao DD, Zohny ZS, Tran DD, Marcus DS, Fouke SJ, Campian JL, Dunn GP, Miller CA, Kim AH. Multisector whole-exome sequencing of newly diagnosed glioblastoma reveals profound intratumoral heterogeneity – Implications for precision medicine. Neuro-Oncology 2018 Mar 27;20(4):472-483

  • Raman H, Santanam L, Vellimana AK, Drzymala RE, Tsien C, Zipfel GJ. Staged Completion of Gamma Knife Radiosurgery Treatment after Unplanned Interruption – Technical Note. Acta Neurochirurgica 2018 Jul;160(7):1343-1347

  • Arias EJ, Bruck B, Vellimana AK, Eby C, Reynolds MR, Blinder MA, Zipfel GJ. Plasmapheresis for Management of Antiphospholipid Syndrome in the Neurosurgical Patient. Operative Neurosurgery Oper Neurosurg (Hagerstown). 2018 May 24

  • A Novel Fluoroscent Imaging Technique for Assessment of Cerebral Vasospasm after Experimental Subarachnoid Hemorrhage. Scientific Reports. 2017 Aug 22;7(1):9126

  • Roland JL, Griffin N, Hacker CD, Vellimana AK, Akbari SH, Shimony JS, Smyth MD, Leuthardt EC, Limbrick DD. Resting State Functional Magnetic Resonance Imaging for Surgical Planning in Pediatric Patients. Journal of Neurosurgery: Pediatrics 2017 Sep 29:1-8. doi: 10.3171/2017.6.PEDS1711. [Epub ahead of print]

  • Leuthardt EC, Perez-Carrillo GJG, Bandt SK, Hacker C, Marcus D, Vellimana A, Limbrick D, Roland J, Miller-Thomas M, Shimony J, Benzinger TLS. Integration of Resting State Functional MRI into Clinical Practice - A Large Single Institution Experience. PloS ONE 018 Jun 22;13(6)

  • Perez-Carrillo GJG, Schweteye KE, Ponisio MR, Vellimana AK, Speidel B, Owen C, McKinstry RC, Smyth MD. Focal Cortical Dysplasia: Clinical Review, Practical Imaging Paradigm and Pearls. American Journal of Neuroradiology

  • Perez-Carrillo GJG, Owen C, Schweteye KE, McFarlane S, Mar S, Vellimana AK, Miller-Thomas M, Shimony J, Smyth MD, Benzinger TLS. Use of hippocampal volumetric measurements to improve diagnostic accuracy in MTS: Case-controlled evaluation. Journal of Neurosurgery: Pediatrics  2017 Mar 24:1-9.

  • Smyth MD, Vellimana AK, Asano E, Sood S. Corpus Callosotomy – Open and Endoscopic Surgical Techniques. Epilepsia, 2017 Apr;58 Suppl 1:73-79.

  • Jeong A, Strahle J, Vellimana AK, Limbrick DD Jr, Smyth MD, Bertrand M. Hemispherotomy in children with electrical status epilepticus of sleep. Journal of Neurosurgery:Pediatrics, 2016 Oct 28: 1-7.

  • Vellimana AK, Washington CW, Yarbrough CK, Washington CW, Pilgram TK, Hoh BL, Derdeyn CP, Zipfel GJ. Intravenous thrombolysis is an independent risk factor for poor outcome after carotid revascularization: evidence from the nationwide inpatient sample. Neurosurgery 2017 Nov 10. doi: 10.1093/neuros/nyx551.

  • Washington CW, Derdeyn CP, Dhar R, Arias EJ, Chicoine MR, Cross DT, Dacey Jr RG, Han BH, Moran CJ, Rich KM, Vellimana AK, Zipfel GJ. A Phase-I proof of concept and safety trial of Sildenafil to treat cerebral vasospasm following subarachnoid hemorrhage. Journal of Neurosurgery, 2015 Aug 28:1-10

  • Vellimana AK, Dunn GP, Dunn I. Intracranial ependymomas in adults. Youmans Textbook of Neurological Surgery (Book Chapter). In press.
  • Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice. Han BH, Zhou ML, Johnson AW, Singh I, Liao F, Vellimana AK, Nelson JW, Milner E, Cirrito JR, Basak J, Yoo M, Dietrich HH, Holtzman DM, Zipfel GJ. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):E881-90. doi: 10.1073/pnas.1414930112. Epub 2015 Feb 9.
  • Cerebral amyloid angiopathy increases susceptibility to infarction after focal cerebral ischemia in Tg2576 mice. Milner E, Zhou ML, Johnson AW, Vellimana AK, Greenberg JK, Holtzman DM, Han BH, Zipfel GJ. Stroke. 2014 Oct;45(10):3064-9. doi: 10.1161/STROKEAHA.114.006078. Epub 2014 Sep 4.
  • Dural arteriovenous fistulas associated with benign meningeal tumors. Vellimana AK, Daniels DJ, Shah MN, Zipfel GJ, Lanzino G. Acta Neurochir (Wien). 2014 Mar;156(3):535-44. doi: 10.1007/s00701-013-1946-z. Epub 2013 Dec 22.
  • Intravenous tissue-type plasminogen activator therapy is an independent risk factor for symptomatic intracerebral hemorrhage after carotid endarterectomy. Vellimana AK, Yarbrough CK, Blackburn S, Strom RG, Pilgram TK, Lee JM, Grubb RL Jr, Rich KM, Chicoine MR, Dacey RG Jr, Derdeyn CP, Zipfel GJ. Neurosurgery. 2014 Mar;74(3):254-61. doi: 10.1227/NEU.0000000000000261.
  • Transient Obstructive Hydrocephalus due to Intraventricular Hemorrhage: A Case Report and Review of Literature. Lusis EA, Vellimana AK, Ray WZ, Chicoine MR, Jost SC. J Clin Neurol. 2013 Jul;9(3):192-5. doi: 10.3988/jcn.2013.9.3.192. Epub 2013 Jul 1.
  • Intracranial hemorrhage from dural arteriovenous fistulas: clinical features and outcome. Daniels DJ, Vellimana AK, Zipfel GJ, Lanzino G. Neurosurg Focus. 2013 May;34(5):E15. doi: 10.3171/2013.4.FOCUS1335. Review.
  • Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model. Vellimana AK, Recinos VR, Hwang L, Fowers KD, Li KW, Zhang Y, Okonma S, Eberhart CG, Brem H, Tyler BM. J Neurooncol. 2013 Feb;111(3):229-36. doi: 10.1007/s11060-012-1014-1. Epub 2012 Dec 7.
  • Symptomatic patients with intraluminal carotid artery thrombus: outcome with a strategy of initial anticoagulation. Vellimana AK, Kadkhodayan Y, Rich KM, Cross DT 3rd, Moran CJ, Zazulia AR, Lee JM, Chicoine MR, Dacey RG Jr, Derdeyn CP, Zipfel GJ. J Neurosurg. 2013 Jan;118(1):34-41. doi: 10.3171/2012.9.JNS12406. Epub 2012 Oct 12.
  • Potential implications of HCN channel dysfunction after subarachnoid hemorrhage. Vellimana AK. J Neurosci. 2012 Jul 4;32(27):9117-8. doi: 10.1523/JNEUROSCI.2064-12.2012.
  • Resorufin analogs preferentially bind cerebrovascular amyloid: potential use as imaging ligands for cerebral amyloid angiopathy. Han BH, Zhou ML, Vellimana AK, Milner E, Kim DH, Greenberg JK, Chu W, Mach RH, Zipfel GJ. Mol Neurodegener. 2011 Dec 22;6:86. doi: 10.1186/1750-1326-6-86.
  • The current surgical management of intracranial aneurysms. Washington CW, Vellimana AK, Zipfel GJ, Dacey RG. J Neurosurg Sci. 2011 Sep;55(3):211-31. Review.
  • Phosphodiesterase 5 inhibition attenuates cerebral vasospasm and improves functional recovery after experimental subarachnoid hemorrhage. Han BH, Vellimana AK, Zhou ML, Milner E, Zipfel GJ. Neurosurgery. 2012 Jan;70(1):178-86; discussion 186-7. doi: 10.1227/NEU.0b013e31822ec2b0.
  • Symptomatic intracranial arterial disease: incidence, natural history, diagnosis, and management. Vellimana AK, Ford AL, Lee JM, Derdeyn CP, Zipfel GJ. Neurosurg Focus. 2011 Jun;30(6):E14. doi: 10.3171/2011.3.FOCUS1138. Review.
  • Endothelial nitric oxide synthase mediates endogenous protection against subarachnoid hemorrhage-induced cerebral vasospasm. Vellimana AK, Milner E, Azad TD, Harries MD, Zhou ML, Gidday JM, Han BH, Zipfel GJ. Stroke. 2011 Mar;42(3):776-82. doi: 10.1161/STROKEAHA.110.607200. Epub 2011 Feb 11.
  • Radiographic and clinical evaluation of free-hand placement of C-2 pedicle screws. Clinical article. Sciubba DM, Noggle JC, Vellimana AK, Alosh H, McGirt MJ, Gokaslan ZL, Wolinsky JP. J Neurosurg Spine. 2009 Jul;11(1):15-22. doi: 10.3171/2009.3.SPINE08166.